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Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model

BACKGROUND: Pendred syndrome, an autosomal-recessive disorder characterized by deafness and goiter, is caused by a mutation of SLC26A4, which codes for the anion exchanger pendrin. We investigated the relationship between pendrin expression and deafness using mice that have (Slc26a4(+/+ )or Slc26a4(...

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Detalles Bibliográficos
Autores principales: Jabba, Sairam V, Oelke, Alisha, Singh, Ruchira, Maganti, Rajanikanth J, Fleming, Sherry, Wall, Susan M, Everett, Lorraine A, Green, Eric D, Wangemann, Philine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796619/
https://www.ncbi.nlm.nih.gov/pubmed/17187680
http://dx.doi.org/10.1186/1741-7015-4-37