Quantification of human bocavirus in lower respiratory tract infections in China

A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, w...

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Detalles Bibliográficos
Autores principales: Lin, Feng, Zeng, Aiping, Yang, Ningmin, Lin, Haiyan, Yang, En, Wang, Shengqi, Pintel, David, Qiu, Jianming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796861/
https://www.ncbi.nlm.nih.gov/pubmed/17266760
http://dx.doi.org/10.1186/1750-9378-2-3
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author Lin, Feng
Zeng, Aiping
Yang, Ningmin
Lin, Haiyan
Yang, En
Wang, Shengqi
Pintel, David
Qiu, Jianming
author_facet Lin, Feng
Zeng, Aiping
Yang, Ningmin
Lin, Haiyan
Yang, En
Wang, Shengqi
Pintel, David
Qiu, Jianming
author_sort Lin, Feng
collection PubMed
description A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, with genomic copies that ranged from 8.0 × 10(3 )to 8.0 × 10(9 )in the samples. The main clinical symptom of patients who were positive for HBoV DNA was a pneumonia-like syndrome represented by high fever and cough. Our results suggest that HBoV may be an important etiological agent of LRTI in children in China.
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spelling pubmed-17968612007-02-10 Quantification of human bocavirus in lower respiratory tract infections in China Lin, Feng Zeng, Aiping Yang, Ningmin Lin, Haiyan Yang, En Wang, Shengqi Pintel, David Qiu, Jianming Infect Agent Cancer Short Report A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, with genomic copies that ranged from 8.0 × 10(3 )to 8.0 × 10(9 )in the samples. The main clinical symptom of patients who were positive for HBoV DNA was a pneumonia-like syndrome represented by high fever and cough. Our results suggest that HBoV may be an important etiological agent of LRTI in children in China. BioMed Central 2007-01-31 /pmc/articles/PMC1796861/ /pubmed/17266760 http://dx.doi.org/10.1186/1750-9378-2-3 Text en Copyright © 2007 Lin et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Report
Lin, Feng
Zeng, Aiping
Yang, Ningmin
Lin, Haiyan
Yang, En
Wang, Shengqi
Pintel, David
Qiu, Jianming
Quantification of human bocavirus in lower respiratory tract infections in China
title Quantification of human bocavirus in lower respiratory tract infections in China
title_full Quantification of human bocavirus in lower respiratory tract infections in China
title_fullStr Quantification of human bocavirus in lower respiratory tract infections in China
title_full_unstemmed Quantification of human bocavirus in lower respiratory tract infections in China
title_short Quantification of human bocavirus in lower respiratory tract infections in China
title_sort quantification of human bocavirus in lower respiratory tract infections in china
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796861/
https://www.ncbi.nlm.nih.gov/pubmed/17266760
http://dx.doi.org/10.1186/1750-9378-2-3
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