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Cross-Reactive Neuraminidase Antibodies Afford Partial Protection against H5N1 in Mice and Are Present in Unexposed Humans
BACKGROUND: A pandemic H5N1 influenza outbreak would be facilitated by an absence of immunity to the avian-derived virus in the human population. Although this condition is likely in regard to hemagglutinin-mediated immunity, the neuraminidase (NA) of H5N1 viruses (avN1) and of endemic human H1N1 vi...
Autores principales: | Sandbulte, Matthew R, Jimenez, Gretchen S, Boon, Adrianus C. M, Smith, Larry R, Treanor, John J, Webby, Richard J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796909/ https://www.ncbi.nlm.nih.gov/pubmed/17298168 http://dx.doi.org/10.1371/journal.pmed.0040059 |
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