p66 Shc and tyrosine-phosphorylated Shc in primary breast tumors identify patients likely to relapse despite tamoxifen therapy

INTRODUCTION: Shc adapter proteins are secondary messenger proteins involved in various cellular pathways, including those mediating receptor tyrosine kinase signaling and apoptosis in response to stress. We have previously reported that high levels of tyrosine-phosphorylated Shc (PY-Shc) and low le...

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Detalles Bibliográficos
Autores principales: Frackelton, A Raymond, Lu, Li, Davol, Pamela A, Bagdasaryan, Robert, Hafer, Laurie J, Sgroi, Dennis C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797038/
https://www.ncbi.nlm.nih.gov/pubmed/17196107
http://dx.doi.org/10.1186/bcr1631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797038/
https://www.ncbi.nlm.nih.gov/pubmed/17196107
http://dx.doi.org/10.1186/bcr1631

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