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MR imaging of therapy-induced changes of bone marrow
MR imaging of bone marrow infiltration by hematologic malignancies provides non-invasive assays of bone marrow cellularity and vascularity to supplement the information provided by bone marrow biopsies. This article will review the MR imaging findings of bone marrow infiltration by hematologic malig...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Springer-Verlag
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797072/ https://www.ncbi.nlm.nih.gov/pubmed/17021706 http://dx.doi.org/10.1007/s00330-006-0404-1 |
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author | Daldrup-Link, Heike E. Henning, Tobias Link, Thomas M. |
author_facet | Daldrup-Link, Heike E. Henning, Tobias Link, Thomas M. |
author_sort | Daldrup-Link, Heike E. |
collection | PubMed |
description | MR imaging of bone marrow infiltration by hematologic malignancies provides non-invasive assays of bone marrow cellularity and vascularity to supplement the information provided by bone marrow biopsies. This article will review the MR imaging findings of bone marrow infiltration by hematologic malignancies with special focus on treatment effects. MR imaging findings of the bone marrow after radiation therapy and chemotherapy will be described. In addition, changes in bone marrow microcirculation and metabolism after anti-angiogenesis treatment will be reviewed. Finally, new specific imaging techniques for the depiction of regulatory events that control blood vessel growth and cell proliferation will be discussed. Future developments are directed to yield comprehensive information about bone marrow structure, function and microenvironment. |
format | Text |
id | pubmed-1797072 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-17970722007-02-13 MR imaging of therapy-induced changes of bone marrow Daldrup-Link, Heike E. Henning, Tobias Link, Thomas M. Eur Radiol Musculoskeletal MR imaging of bone marrow infiltration by hematologic malignancies provides non-invasive assays of bone marrow cellularity and vascularity to supplement the information provided by bone marrow biopsies. This article will review the MR imaging findings of bone marrow infiltration by hematologic malignancies with special focus on treatment effects. MR imaging findings of the bone marrow after radiation therapy and chemotherapy will be described. In addition, changes in bone marrow microcirculation and metabolism after anti-angiogenesis treatment will be reviewed. Finally, new specific imaging techniques for the depiction of regulatory events that control blood vessel growth and cell proliferation will be discussed. Future developments are directed to yield comprehensive information about bone marrow structure, function and microenvironment. Springer-Verlag 2006-09-21 2007-03 /pmc/articles/PMC1797072/ /pubmed/17021706 http://dx.doi.org/10.1007/s00330-006-0404-1 Text en © Springer-Verlag 2006 |
spellingShingle | Musculoskeletal Daldrup-Link, Heike E. Henning, Tobias Link, Thomas M. MR imaging of therapy-induced changes of bone marrow |
title | MR imaging of therapy-induced changes of bone marrow |
title_full | MR imaging of therapy-induced changes of bone marrow |
title_fullStr | MR imaging of therapy-induced changes of bone marrow |
title_full_unstemmed | MR imaging of therapy-induced changes of bone marrow |
title_short | MR imaging of therapy-induced changes of bone marrow |
title_sort | mr imaging of therapy-induced changes of bone marrow |
topic | Musculoskeletal |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797072/ https://www.ncbi.nlm.nih.gov/pubmed/17021706 http://dx.doi.org/10.1007/s00330-006-0404-1 |
work_keys_str_mv | AT daldruplinkheikee mrimagingoftherapyinducedchangesofbonemarrow AT henningtobias mrimagingoftherapyinducedchangesofbonemarrow AT linkthomasm mrimagingoftherapyinducedchangesofbonemarrow |