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The Role of Myelin in Theiler's Virus Persistence in the Central Nervous System
Theiler's virus, a picornavirus, persists for life in the central nervous system of mouse and causes a demyelinating disease that is a model for multiple sclerosis. The virus infects neurons first but persists in white matter glial cells, mainly oligodendrocytes and macrophages. The mechanism,...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797621/ https://www.ncbi.nlm.nih.gov/pubmed/17305428 http://dx.doi.org/10.1371/journal.ppat.0030023 |