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The Role of Myelin in Theiler's Virus Persistence in the Central Nervous System

Theiler's virus, a picornavirus, persists for life in the central nervous system of mouse and causes a demyelinating disease that is a model for multiple sclerosis. The virus infects neurons first but persists in white matter glial cells, mainly oligodendrocytes and macrophages. The mechanism,...

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Detalles Bibliográficos
Autores principales:	Roussarie, Jean-Pierre, Ruffié, Claude, Brahic, Michel
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797621/ https://www.ncbi.nlm.nih.gov/pubmed/17305428 http://dx.doi.org/10.1371/journal.ppat.0030023

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