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Complex effects of rexinoids on ligand dependent activation or inhibition of the xenobiotic receptor, CAR

BACKGROUND: CAR/RXR heterodimers bind a variety of hormone response elements and activate transcription in the absence of added ligands. This constitutive activity of murine CAR can be inhibited by the inverse agonist ligand androstanol or increased by the agonist TCPOBOP. RXR agonists activate some...

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Detalles Bibliográficos
Autores principales:	Tzameli, Iphigenia, Chua, Steven S, Cheskis, Boris, Moore, David D
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2003
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC179875/ https://www.ncbi.nlm.nih.gov/pubmed/12904257 http://dx.doi.org/10.1186/1478-1336-1-2

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