ERβ Binds N-CoR in the Presence of Estrogens via an LXXLL-like Motif in the N-CoR C-terminus

Nuclear receptors (NRs) usually bind the corepressors N-CoR and SMRT in the absence of ligand or in the presence of antagonists. Agonist binding leads to corepressor release and recruitment of coactivators. Here, we report that estrogen receptor β (ERβ) binds N-CoR and SMRT in the presence of agonis...

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Detalles Bibliográficos
Autores principales: Webb, Paul, Valentine, Cathleen, Nguyen, Phuong, Price, Richard H, Marimuthu, Adhirai, West, Brian L, Baxter, John D, Kushner, Peter J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC179877/
https://www.ncbi.nlm.nih.gov/pubmed/12904255
http://dx.doi.org/10.1186/1478-1336-1-4

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