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Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery

BACKGROUND: The cytotoxicity and the rejoining of DNA double-strand breaks induced by γ-rays, H(2)O(2 )and neocarzinostatin, were investigated in normal and PARP-1 knockout mouse 3T3 fibroblasts to determine the role of poly(ADP-ribose) polymerase (PARP-1) in DNA double-strand break repair. RESULTS:...

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Detalles Bibliográficos
Autores principales:	Noël, Georges, Giocanti, Nicole, Fernet, Marie, Mégnin-Chanet, Frédérique, Favaudon, Vincent
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2003
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC179890/ https://www.ncbi.nlm.nih.gov/pubmed/12866953 http://dx.doi.org/10.1186/1471-2121-4-7

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