Expression of Cyclins A, E and Topoisomerase II α correlates with centrosome amplification and genomic instability and influences the reliability of cytometric S-phase determination

BACKGROUND: The progression of normal cells through the cell cycle is meticulously regulated by checkpoints guaranteeing the exact replication of the genome during S-phase and its equal division at mitosis. A prerequisite for this achievement is synchronized DNA-replication and centrosome duplicatio...

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Detalles Bibliográficos
Autores principales: Kronenwett, Ulrike, Castro, Juan, Roblick, Uwe J, Fujioka, Kaoru, Östring, Carin, Faridmoghaddam, Farinaz, Laytragoon-Lewin, Nongnit, Tribukait, Bernhard, Auer, Gert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC179891/
https://www.ncbi.nlm.nih.gov/pubmed/12875657
http://dx.doi.org/10.1186/1471-2121-4-8

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