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Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression
BACKGROUND: Fasting and diabetes are characterized by elevated glucocorticoids and reduced insulin, leptin, elevated hypothalamic AGRP and NPY mRNA, and reduced hypothalamic POMC mRNA. Although leptin replacement can reverse changes in hypothalamic gene expression associated with fasting and diabete...
Autores principales: | Makimura, Hideo, Mizuno, Tooru M, Isoda, Fumiko, Beasley, Joe, Silverstein, Jeffrey H, Mobbs, Charles V |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC179893/ https://www.ncbi.nlm.nih.gov/pubmed/12848900 http://dx.doi.org/10.1186/1472-6793-3-5 |
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