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PPARα Deficiency in Inflammatory Cells Suppresses Tumor Growth
Inflammation in the tumor bed can either promote or inhibit tumor growth. Peroxisome proliferator-activated receptor (PPAR)α is a central transcriptional suppressor of inflammation, and may therefore modulate tumor growth. Here we show that PPARα deficiency in the host leads to overt inflammation th...
Autores principales: | Kaipainen, Arja, Kieran, Mark W., Huang, Sui, Butterfield, Catherine, Bielenberg, Diane, Mostoslavsky, Gustavo, Mulligan, Richard, Folkman, Judah, Panigrahy, Dipak |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800345/ https://www.ncbi.nlm.nih.gov/pubmed/17327920 http://dx.doi.org/10.1371/journal.pone.0000260 |
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