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A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology
BACKGROUND: Immunity against the bovine protozoan parasite Theileria parva has previously been shown to be mediated through lysis of parasite-infected cells by MHC class I restricted CD8(+ )cytotoxic T lymphocytes. It is hypothesized that identification of CTL target schizont antigens will aid the d...
Autores principales: | Graham, Simon P, Honda, Yoshikazu, Pellé, Roger, Mwangi, Duncan M, Glew, E Jane, de Villiers, Etienne P, Shah, Trushar, Bishop, Richard, van der Bruggen, Pierre, Nene, Vishvanath, Taracha, Evans LN |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802067/ https://www.ncbi.nlm.nih.gov/pubmed/17291333 http://dx.doi.org/10.1186/1745-7580-3-2 |
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