Cargando…
Use of modified U1 snRNAs to inhibit HIV-1 replication
Control of RNA processing plays a central role in regulating the replication of HIV-1, in particular the 3′ polyadenylation of viral RNA. Based on the demonstration that polyadenylation of mRNAs can be disrupted by the targeted binding of modified U1 snRNA, we examined whether binding of U1 snRNAs t...
Autores principales: | Sajic, R., Lee, K., Asai, K., Sakac, D., Branch, D. R., Upton, C., Cochrane, A. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802557/ https://www.ncbi.nlm.nih.gov/pubmed/17158512 http://dx.doi.org/10.1093/nar/gkl1022 |
Ejemplares similares
-
Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease
por: Vazquez-Arango, Pilar, et al.
Publicado: (2016) -
The U1, U2 and U5 snRNAs crosslink to the 5′ exon during yeast pre-mRNA splicing
por: McGrail, Joanne C., et al.
Publicado: (2008) -
RBM7 subunit of the NEXT complex binds U-rich sequences and targets 3′-end extended forms of snRNAs
por: Hrossova, Dominika, et al.
Publicado: (2015) -
Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs
por: Li, Zhihua, et al.
Publicado: (2012) -
Evolutionarily divergent spliceosomal snRNAs and a conserved non-coding RNA processing motif in Giardia lamblia
por: Hudson, Andrew J., et al.
Publicado: (2012)