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p53 and p73 display common and distinct requirements for sequence specific binding to DNA

Although p53 and p73 share considerable homology in their DNA-binding domains, there have been few studies examining their relative interactions with DNA as purified proteins. Comparing p53 and p73β proteins, our data show that zinc chelation by EDTA is significantly more detrimental to the ability...

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Detalles Bibliográficos
Autores principales: Lokshin, Maria, Li, Yingchun, Gaiddon, Christian, Prives, Carol
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802567/
https://www.ncbi.nlm.nih.gov/pubmed/17170001
http://dx.doi.org/10.1093/nar/gkl1047