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Improved nuclear localization of DNA-binding polyamides

Regulation of endogenous genes by DNA-binding polyamides requires effective nuclear localization. Previous work employing confocal microscopy to study uptake of fluorophore-labeled polyamides has demonstrated the difficulty of predicting a priori the nuclear uptake of a given polyamide. The data sug...

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Detalles Bibliográficos
Autores principales:	Nickols, Nicholas G., Jacobs, Claire S., Farkas, Michelle E., Dervan, Peter B.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802595/ https://www.ncbi.nlm.nih.gov/pubmed/17175539 http://dx.doi.org/10.1093/nar/gkl1042

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