Structural basis for sequence-dependent DNA cleavage by nonspecific endonucleases

Nonspecific endonucleases hydrolyze DNA without sequence specificity but with sequence preference, however the structural basis for cleavage preference remains elusive. We show here that the nonspecific endonuclease ColE7 cleaves DNA with a preference for making nicks after (at 3′O-side) thymine bas...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yi-Ting, Yang, Wei-Jen, Li, Chia-Lung, Doudeva, Lyudmila G., Yuan, Hanna S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802626/
https://www.ncbi.nlm.nih.gov/pubmed/17175542
http://dx.doi.org/10.1093/nar/gkl621

Ejemplares similares

Ejemplares similares