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Elevated Rates of Sister Chromatid Exchange at Chromosome Ends
Chromosome ends are known hotspots of meiotic recombination and double-strand breaks. We monitored mitotic sister chromatid exchange (SCE) in telomeres and subtelomeres and found that 17% of all SCE occurs in the terminal 0.1% of the chromosome. Telomeres and subtelomeres are significantly enriched...
Autores principales: | Rudd, M. Katharine, Friedman, Cynthia, Parghi, Sean S, Linardopoulou, Elena V, Hsu, Li, Trask, Barbara J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802831/ https://www.ncbi.nlm.nih.gov/pubmed/17319749 http://dx.doi.org/10.1371/journal.pgen.0030032 |
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