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A Link between Virulence and Homeostatic Responses to Hypoxia during Infection by the Human Fungal Pathogen Cryptococcus neoformans
Fungal pathogens of humans require molecular oxygen for several essential biochemical reactions, yet virtually nothing is known about how they adapt to the relatively hypoxic environment of infected tissues. We isolated mutants defective in growth under hypoxic conditions, but normal for growth in n...
Autores principales: | Chun, Cheryl D, Liu, Oliver W, Madhani, Hiten D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1803011/ https://www.ncbi.nlm.nih.gov/pubmed/17319742 http://dx.doi.org/10.1371/journal.ppat.0030022 |
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