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Cytosolic 5′-Triphosphate Ended Viral Leader Transcript of Measles Virus as Activator of the RIG I-Mediated Interferon Response

BACKGROUND: Double stranded RNA (dsRNA) is widely accepted as an RNA motif recognized as a danger signal by the cellular sentries. However, the biology of non-segmented negative strand RNA viruses, or Mononegavirales, is hardly compatible with the production of such dsRNA. METHODOLOGY AND PRINCIPAL...

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Detalles Bibliográficos
Autores principales:	Plumet, Sébastien, Herschke, Florence, Bourhis, Jean-Marie, Valentin, Hélène, Longhi, Sonia, Gerlier, Denis
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1804102/ https://www.ncbi.nlm.nih.gov/pubmed/17356690 http://dx.doi.org/10.1371/journal.pone.0000279

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