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Transient severe metastatic calcification in acute renal failure

Metastatic calcification, a known complication of prolonged end-stage renal disease, is herein described for the first time in a 10-month-old boy with acute renal failure, manifesting as a painful and swollen arm. Imaging revealed diffuse calcification and technetium-99 methylene diphosphonate ((99)...

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Detalles Bibliográficos
Autores principales: Landau, Daniel, Krymko, Hanna, Shalev, Hanna, Agronovich, Svetlana
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805049/
https://www.ncbi.nlm.nih.gov/pubmed/17186278
http://dx.doi.org/10.1007/s00467-006-0387-9
Descripción
Sumario:Metastatic calcification, a known complication of prolonged end-stage renal disease, is herein described for the first time in a 10-month-old boy with acute renal failure, manifesting as a painful and swollen arm. Imaging revealed diffuse calcification and technetium-99 methylene diphosphonate ((99)Tc-MDP) uptake around the humerus and axilla. Calcium and vitamin D restriction, followed by intravenous administration of sodium thiosulfate caused a full symptomatic, radio- and scintigraphic improvement.