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CT/MRI of neuroendocrine tumours

Neuroendocrine tumours (NETs) are often thought to be rare and rather recherché cancers which are of little concern to the general physician, surgeon or radiologist because of their rarity and esoteric nature. In fact, while relatively uncommon, the total group of gastro-entero-pancreatic (GEP) tumo...

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Autor principal: Reznek, Rodney H
Formato: Texto
Lenguaje:English
Publicado: e-MED 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805060/
https://www.ncbi.nlm.nih.gov/pubmed/17114072
http://dx.doi.org/10.1102/1470-7330.2006.9037
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author Reznek, Rodney H
author_facet Reznek, Rodney H
author_sort Reznek, Rodney H
collection PubMed
description Neuroendocrine tumours (NETs) are often thought to be rare and rather recherché cancers which are of little concern to the general physician, surgeon or radiologist because of their rarity and esoteric nature. In fact, while relatively uncommon, the total group of gastro-entero-pancreatic (GEP) tumours incorporates the spectrum of all types of carcinoids, incuding bronchial carcinoids, and the whole gamut of islet-cell tumours. Some of these may present as functioning tumours, with a plethora of hormonal secretions and concomitant clinical syndromes, and GEPs in general have an incidence around 30 per million population per year. This means that in the whole European Union, for example, there will be in the region of 12000 new patients every year presenting with one or another manifestation of these tumours. Furthermore, the comparatively long survival of many of these patients, compared to more common adenocarcinomas or epithelial tumours, implies that the point prevalence is also not inconsiderable. However, it is undoubtedly true that these tumours can be difficult to identify, especially in their early stages, and it is then that radiological investigation becomes of paramount importance. Having taken into account all these considerations, most investigators would initiate investigation of a suspected or biochemically proven islet-cell tumour with cross-sectional imaging—either CT or MRI. This will clearly identify the larger lesions, allow assessment of the entire abdomen, and provide valuable information on the presence of hepatic metastates.
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spelling pubmed-18050602008-10-31 CT/MRI of neuroendocrine tumours Reznek, Rodney H Cancer Imaging Article Neuroendocrine tumours (NETs) are often thought to be rare and rather recherché cancers which are of little concern to the general physician, surgeon or radiologist because of their rarity and esoteric nature. In fact, while relatively uncommon, the total group of gastro-entero-pancreatic (GEP) tumours incorporates the spectrum of all types of carcinoids, incuding bronchial carcinoids, and the whole gamut of islet-cell tumours. Some of these may present as functioning tumours, with a plethora of hormonal secretions and concomitant clinical syndromes, and GEPs in general have an incidence around 30 per million population per year. This means that in the whole European Union, for example, there will be in the region of 12000 new patients every year presenting with one or another manifestation of these tumours. Furthermore, the comparatively long survival of many of these patients, compared to more common adenocarcinomas or epithelial tumours, implies that the point prevalence is also not inconsiderable. However, it is undoubtedly true that these tumours can be difficult to identify, especially in their early stages, and it is then that radiological investigation becomes of paramount importance. Having taken into account all these considerations, most investigators would initiate investigation of a suspected or biochemically proven islet-cell tumour with cross-sectional imaging—either CT or MRI. This will clearly identify the larger lesions, allow assessment of the entire abdomen, and provide valuable information on the presence of hepatic metastates. e-MED 2006-10-31 /pmc/articles/PMC1805060/ /pubmed/17114072 http://dx.doi.org/10.1102/1470-7330.2006.9037 Text en Copyright © 2006 International Cancer Imaging Society
spellingShingle Article
Reznek, Rodney H
CT/MRI of neuroendocrine tumours
title CT/MRI of neuroendocrine tumours
title_full CT/MRI of neuroendocrine tumours
title_fullStr CT/MRI of neuroendocrine tumours
title_full_unstemmed CT/MRI of neuroendocrine tumours
title_short CT/MRI of neuroendocrine tumours
title_sort ct/mri of neuroendocrine tumours
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805060/
https://www.ncbi.nlm.nih.gov/pubmed/17114072
http://dx.doi.org/10.1102/1470-7330.2006.9037
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