Progranulin in frontotemporal lobar degeneration and neuroinflammation

Progranulin (PGRN) is a pleiotropic protein that has gained the attention of the neuroscience community with recent discoveries of mutations in the gene for PGRN that cause frontotemporal lobar degeneration (FTLD). Pathogenic mutations in PGRN result in null alleles, and the disease is likely the re...

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Detalles Bibliográficos
Autores principales: Ahmed, Zeshan, Mackenzie, Ian RA, Hutton, Michael L, Dickson, Dennis W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805428/
https://www.ncbi.nlm.nih.gov/pubmed/17291356
http://dx.doi.org/10.1186/1742-2094-4-7

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