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8-epi-Salvinorin B: crystal structure and affinity at the κ opioid receptor

There have been many reports of epimerization of salvinorins at C-8 under basic conditions, but little evidence has been presented to establish the structure of these compounds. We report here the first crystal structure of an 8-epi-salvinorin or derivative: the title compound, 2b. The lactone adopt...

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Detalles Bibliográficos
Autores principales: Munro, Thomas A, Duncan, Katharine K, Staples, Richard J, Xu, Wei, Liu-Chen, Lee-Yuan, Béguin, Cécile, Carlezon, William A, Cohen, Bruce M
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805503/
https://www.ncbi.nlm.nih.gov/pubmed/17212822
http://dx.doi.org/10.1186/1860-5397-3-1

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