The Delta intracellular domain mediates TGF-β/Activin signaling through binding to Smads and has an important bi-directional function in the Notch–Delta signaling pathway

Delta is a major transmembrane ligand for Notch receptor that mediates numerous cell fate decisions. The Notch signaling pathway has long been thought to be mono-directional, because ligands for Notch were generally believed to be unable to transmit signals into the cells expressing them. However, w...

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Detalles Bibliográficos
Autores principales: Hiratochi, Masahiro, Nagase, Hisashi, Kuramochi, Yu, Koh, Chang-Sung, Ohkawara, Takeshi, Nakayama, Kohzo
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807952/
https://www.ncbi.nlm.nih.gov/pubmed/17251195
http://dx.doi.org/10.1093/nar/gkl1128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807952/
https://www.ncbi.nlm.nih.gov/pubmed/17251195
http://dx.doi.org/10.1093/nar/gkl1128

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