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The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing

The nucleolar protein Pes1 interacts with Bop1 and WDR12 in a stable complex (PeBoW-complex) and its expression is tightly associated with cell proliferation. The yeast homologue Nop7p (Yph1p) functions in both, rRNA processing and cell cycle progression. The presence of a BRCT-domain (BRCA1 C-termi...

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Detalles Bibliográficos
Autores principales:	Hölzel, Michael, Grimm, Thomas, Rohrmoser, Michaela, Malamoussi, Anastassia, Harasim, Thomas, Gruber-Eber, Anita, Kremmer, Elisabeth, Eick, Dirk
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807956/ https://www.ncbi.nlm.nih.gov/pubmed/17189298 http://dx.doi.org/10.1093/nar/gkl1058

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