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Resequencing of genes for transforming growth factor β1 (TGFB1) type 1 and 2 receptors (TGFBR1, TGFBR2), and association analysis of variants with diabetic nephropathy

BACKGROUND: Diabetic nephropathy is the leading cause of end stage renal failure in the western world. There is substantial epidemiological evidence supporting a genetic predisposition to diabetic nephropathy, however the exact molecular mechanisms remain unknown. Transforming growth factor (TGFβ1)...

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Detalles Bibliográficos
Autores principales:	McKnight, Amy Jayne, Savage, David A, Patterson, Chris C, Sadlier, Denise, Maxwell, A Peter
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808054/ https://www.ncbi.nlm.nih.gov/pubmed/17319955 http://dx.doi.org/10.1186/1471-2350-8-5

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