Evaluation of a recombinant human gelatin as a substitute for a hydrolyzed porcine gelatin in a refrigerator-stable Oka/Merck live varicella vaccine

BACKGROUND: The labile nature of live, attenuated varicella-zoster virus (Oka/Merck) requires robust stabilization during virus bulk preparation and vaccine manufacturing in order to preserve potency through storage and administration. One stabilizing ingredient used in a varicella-zoster virus (VZV...

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Detalles Bibliográficos
Autores principales: Liska, Vladimir, Bigert, Stacey A, Bennett, Philip S, Olsen, David, Chang, Robert, Burke, Carl J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808055/
https://www.ncbi.nlm.nih.gov/pubmed/17319952
http://dx.doi.org/10.1186/1476-8518-5-4

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