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A Burst-Based “Hebbian” Learning Rule at Retinogeniculate Synapses Links Retinal Waves to Activity-Dependent Refinement

Patterned spontaneous activity in the developing retina is necessary to drive synaptic refinement in the lateral geniculate nucleus (LGN). Using perforated patch recordings from neurons in LGN slices during the period of eye segregation, we examine how such burst-based activity can instruct this ref...

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Detalles Bibliográficos
Autores principales: Butts, Daniel A, Kanold, Patrick O, Shatz, Carla J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808114/
https://www.ncbi.nlm.nih.gov/pubmed/17341130
http://dx.doi.org/10.1371/journal.pbio.0050061