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Precancerous Stem Cells Have the Potential for both Benign and Malignant Differentiation
Cancer stem cells (CSCs) have been identified in hematopoietic and solid tumors. However, their precursors—namely, precancerous stem cells (pCSCs) —have not been characterized. Here we experimentally define the pCSCs that have the potential for both benign and malignant differentiation, depending on...
Autores principales: | Chen, Li, Shen, Rulong, Ye, Yin, Pu, Xin-An, Liu, Xingluo, Duan, Wenrui, Wen, Jing, Zimmerer, Jason, Wang, Ying, Liu, Yan, Lasky, Larry C., Heerema, Nyla A., Perrotti, Danilo, Ozato, Keiko, Kuramochi-Miyagawa, Satomi, Nakano, Toru, Yates, Allen J., Carson III, William E., Lin, Haifan, Barsky, Sanford H., Gao, Jian-Xin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808425/ https://www.ncbi.nlm.nih.gov/pubmed/17356702 http://dx.doi.org/10.1371/journal.pone.0000293 |
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