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Formation of multinucleated giant cells and microglial degeneration in rats expressing a mutant Cu/Zn superoxide dismutase gene

BACKGROUND: Microglial neuroinflammation is thought to play a role in the pathogenesis of amyotrophic lateral sclerosis (ALS). The purpose of this study was to provide a histopathological evaluation of the microglial neuroinflammatory response in a rodent model of ALS, the SOD1(G93A )transgenic rat....

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Detalles Bibliográficos
Autores principales:	Fendrick, Sarah E, Xue, Qing-Shan, Streit, Wolfgang J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808448/ https://www.ncbi.nlm.nih.gov/pubmed/17328801 http://dx.doi.org/10.1186/1742-2094-4-9

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