Modification of a Hydrophobic Layer by a Point Mutation in Syntaxin 1A Regulates the Rate of Synaptic Vesicle Fusion

Both constitutive secretion and Ca(2+)-regulated exocytosis require the assembly of the soluble N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) complexes. At present, little is known about how the SNARE complexes mediating these two distinct pathways differ in structure. Using...

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Detalles Bibliográficos
Autores principales: Lagow, Robert D, Bao, Hong, Cohen, Evan N, Daniels, Richard W, Zuzek, Aleksej, Williams, Wade H, Macleod, Gregory T, Sutton, R. Bryan, Zhang, Bing
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808484/
https://www.ncbi.nlm.nih.gov/pubmed/17341138
http://dx.doi.org/10.1371/journal.pbio.0050072

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