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FMRP Mediates mGluR(5)-Dependent Translation of Amyloid Precursor Protein
Amyloid precursor protein (APP) facilitates synapse formation in the developing brain, while beta-amyloid (Aβ) accumulation, which is associated with Alzheimer disease, results in synaptic loss and impaired neurotransmission. Fragile X mental retardation protein (FMRP) is a cytoplasmic mRNA binding...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808499/ https://www.ncbi.nlm.nih.gov/pubmed/17298186 http://dx.doi.org/10.1371/journal.pbio.0050052 |