Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines

A [3 + 3] annelation of enantiomerically pure aziridine 7 provides the functionalised piperidine 8 that can be elaborated to the indolizidine skeleton in only 4 steps with good stereocontrol.

Detalles Bibliográficos
Autores principales: Provoost, Olivier Y, Hazelwood, Andrew J, Harrity, Joseph P A
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2007
Materias:
Preliminary Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810302/
https://www.ncbi.nlm.nih.gov/pubmed/17288604
http://dx.doi.org/10.1186/1860-5397-3-8
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author Provoost, Olivier Y
Hazelwood, Andrew J
Harrity, Joseph P A
author_facet Provoost, Olivier Y
Hazelwood, Andrew J
Harrity, Joseph P A
author_sort Provoost, Olivier Y
collection PubMed
description A [3 + 3] annelation of enantiomerically pure aziridine 7 provides the functionalised piperidine 8 that can be elaborated to the indolizidine skeleton in only 4 steps with good stereocontrol.
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spelling pubmed-18103022007-03-06 Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines Provoost, Olivier Y Hazelwood, Andrew J Harrity, Joseph P A Beilstein J Org Chem Preliminary Communication A [3 + 3] annelation of enantiomerically pure aziridine 7 provides the functionalised piperidine 8 that can be elaborated to the indolizidine skeleton in only 4 steps with good stereocontrol. Beilstein-Institut 2007-02-08 /pmc/articles/PMC1810302/ /pubmed/17288604 http://dx.doi.org/10.1186/1860-5397-3-8 Text en Copyright © 2007, Provoost et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Preliminary Communication
Provoost, Olivier Y
Hazelwood, Andrew J
Harrity, Joseph P A
Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines
title Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines
title_full Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines
title_fullStr Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines
title_full_unstemmed Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines
title_short Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines
title_sort pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines
topic Preliminary Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810302/
https://www.ncbi.nlm.nih.gov/pubmed/17288604
http://dx.doi.org/10.1186/1860-5397-3-8
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AT hazelwoodandrewj pdcatalysed33annelationsinthestereoselectivesynthesisofindolizidines
AT harrityjosephpa pdcatalysed33annelationsinthestereoselectivesynthesisofindolizidines

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