Heteropolymeric Triplex-Based Genomic Assay® to Detect Pathogens or Single-Nucleotide Polymorphisms in Human Genomic Samples

Human genomic samples are complex and are considered difficult to assay directly without denaturation or PCR amplification. We report the use of a base-specific heteropolymeric triplex, formed by native duplex genomic target and an oligonucleotide third strand probe, to assay for low copy pathogen g...

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Detalles Bibliográficos
Autores principales: Daksis, Jasmine I., Erikson, Glen H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810429/
https://www.ncbi.nlm.nih.gov/pubmed/17375191
http://dx.doi.org/10.1371/journal.pone.0000305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810429/
https://www.ncbi.nlm.nih.gov/pubmed/17375191
http://dx.doi.org/10.1371/journal.pone.0000305

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