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Heteropolymeric Triplex-Based Genomic Assay® to Detect Pathogens or Single-Nucleotide Polymorphisms in Human Genomic Samples

Human genomic samples are complex and are considered difficult to assay directly without denaturation or PCR amplification. We report the use of a base-specific heteropolymeric triplex, formed by native duplex genomic target and an oligonucleotide third strand probe, to assay for low copy pathogen g...

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Detalles Bibliográficos
Autores principales:	Daksis, Jasmine I., Erikson, Glen H.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810429/ https://www.ncbi.nlm.nih.gov/pubmed/17375191 http://dx.doi.org/10.1371/journal.pone.0000305

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