Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells

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BACKGROUND: Many lines of evidence suggest that poly(ADP-ribose) polymerase-1 (Parp-1) is involved in transcriptional regulation of various genes as a coactivator or a corepressor by modulating chromatin structure. However, the impact of Parp-1-deficiency on the regulation of genome-wide gene expres...

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Detalles Bibliográficos
Autores principales: Ogino, Hideki, Nozaki, Tadashige, Gunji, Akemi, Maeda, Miho, Suzuki, Hiroshi, Ohta, Tsutomu, Murakami, Yasufumi, Nakagama, Hitoshi, Sugimura, Takashi, Masutani, Mitsuko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810537/
https://www.ncbi.nlm.nih.gov/pubmed/17286852
http://dx.doi.org/10.1186/1471-2164-8-41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810537/
https://www.ncbi.nlm.nih.gov/pubmed/17286852
http://dx.doi.org/10.1186/1471-2164-8-41

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