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Live Hot, Die Young: Transmission Distortion in Recombination Hotspots

There is strong evidence that hotspots of meiotic recombination in humans are transient features of the genome. For example, hotspot locations are not shared between human and chimpanzee. Biased gene conversion in favor of alleles that locally disrupt hotspots is a possible explanation of the short...

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Detalles Bibliográficos
Autores principales: Coop, Graham, Myers, Simon R
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1817654/
https://www.ncbi.nlm.nih.gov/pubmed/17352536
http://dx.doi.org/10.1371/journal.pgen.0030035