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High serum levels of soluble CD40-L in patients with undifferentiated nasopharyngeal carcinoma: pathogenic and clinical relevance

BACKGROUND: Engagement of CD40 promotes survival of undifferentiated nasopharyngeal carcinoma (UNPC) cells and similar effects are induced by the EBV oncoprotein LMP-1 that is expressed in a fraction of cases. Considering that CD40 may be activated also by the soluble isoform of CD40L (sCD40L), we i...

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Detalles Bibliográficos
Autores principales:	Caggiari, Laura, Guidoboni, Massimo, Vaccher, Emanuela, Barzan, Luigi, Franchin, Giovanni, Gloghini, Annunziata, Martorelli, Debora, Zancai, Paola, Bortolin, Maria Teresa, Mazzucato, Mario, Serraino, Diego, Carbone, Antonino, De Paoli, Paolo, Dolcetti, Riccardo
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1819365/ https://www.ncbi.nlm.nih.gov/pubmed/17331231 http://dx.doi.org/10.1186/1750-9378-2-5

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