Cargando…
FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients
BACKGROUND: In the quest for novel molecular mediators of glioma progression, we studied the regulation of FBXW7 (hCDC4/hAGO/SEL10), its association with survival of patients with glioblastoma and its potential role as a tumor suppressor gene in glioma cells. The F-box protein Fbxw7 is a component o...
Autores principales: | Hagedorn, Martin, Delugin, Maylis, Abraldes, Isabelle, Allain, Nathalie, Belaud-Rotureau, Marc-Antoine, Turmo, Michelle, Prigent, Claude, Loiseau, Hugues, Bikfalvi, Andréas, Javerzat, Sophie |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1819378/ https://www.ncbi.nlm.nih.gov/pubmed/17326833 http://dx.doi.org/10.1186/1747-1028-2-9 |
Ejemplares similares
-
Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer
por: Akhoondi, Shahab, et al.
Publicado: (2010) -
Fbw7/hCDC4 dimerization regulates its substrate interactions
por: Welcker, Markus, et al.
Publicado: (2007) -
Mutation Analysis of hCDC4 in AML Cells Identifies a New Intronic Polymorphism
por: Nowak, Daniel, et al.
Publicado: (2006) -
Chromosomal instability and lack of cyclin E regulation in hCdc4 mutant human breast cancer cells
por: Willmarth, Nicole E, et al.
Publicado: (2004) -
Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity
por: Jabouille, Arnaud, et al.
Publicado: (2015)