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Trans-inhibition of HIV-1 by a long hairpin RNA expressed within the viral genome

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) can be inhibited by means of RNA silencing or interference (RNAi) using synthetic short interfering RNAs (siRNAs) or gene constructs encoding short hairpin RNAs (shRNAs) or long hairpin RNAs (lhRNAs). The use of siRNA and shRNA as antiviral the...

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Detalles Bibliográficos
Autores principales:	Konstantinova, Pavlina, ter Brake, Olivier, Haasnoot, Joost, de Haan, Peter, Berkhout, Ben
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1819390/ https://www.ncbi.nlm.nih.gov/pubmed/17331227 http://dx.doi.org/10.1186/1742-4690-4-15

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