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X-Linked G6PD Deficiency Protects Hemizygous Males but Not Heterozygous Females against Severe Malaria

BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) is important in the control of oxidant stress in erythrocytes, the host cells for Plasmodium falciparum. Mutations in this enzyme produce X-linked deficiency states associated with protection against malaria, notably in Africa where the A− form of...

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Detalles Bibliográficos
Autores principales:	Guindo, Aldiouma, Fairhurst, Rick M, Doumbo, Ogobara K, Wellems, Thomas E, Diallo, Dapa A
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820604/ https://www.ncbi.nlm.nih.gov/pubmed/17355169 http://dx.doi.org/10.1371/journal.pmed.0040066

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