Cargando…
An Aromatic Sensor with Aversion to Damaged Strands Confers Versatility to DNA Repair
It was not known how xeroderma pigmentosum group C (XPC) protein, the primary initiator of global nucleotide excision repair, achieves its outstanding substrate versatility. Here, we analyzed the molecular pathology of a unique Trp690Ser substitution, which is the only reported missense mutation in...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820611/ https://www.ncbi.nlm.nih.gov/pubmed/17355181 http://dx.doi.org/10.1371/journal.pbio.0050079 |