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Silencing of the Pink1 Gene Expression by Conditional RNAi Does Not Induce Dopaminergic Neuron Death in Mice

Transgenic RNAi, an alternative to the gene knockout approach, can induce hypomorphic phenotypes that resemble those of the gene knockout in mice. Conditional transgenic RNAi is an attractive choice of method for reverse genetics in vivo because it can achieve temporal and spatial silencing of targe...

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Detalles Bibliográficos
Autores principales:	Zhou, Hongxia, Falkenburger, Björn H, Schulz, Jörg B, Tieu, Kim, Xu, Zuoshang, Xia, Xu Gang
Formato:	Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2007
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820878/ https://www.ncbi.nlm.nih.gov/pubmed/17389931

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