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Factor analysis for gene regulatory networks and transcription factor activity profiles
BACKGROUND: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription factors (TFs) are proportional to their mRNA levels. This assumption is invalid for most biological systems. However, one mig...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1821042/ https://www.ncbi.nlm.nih.gov/pubmed/17319944 http://dx.doi.org/10.1186/1471-2105-8-61 |