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Cluster of systemic lupus erythematosus (SLE) associated with an oil field waste site: a cross sectional study
BACKGROUND: This is a community comparison study that examines persons living in a subdivision exposed to petroleum products and mercury. METHODS: We compared their health status and questionnaire responses to those living in another community with no known exposures of this type. RESULTS: Pristane...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1821321/ https://www.ncbi.nlm.nih.gov/pubmed/17316448 http://dx.doi.org/10.1186/1476-069X-6-8 |
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author | Dahlgren, James Takhar, Harpreet Anderson-Mahoney, Pamela Kotlerman, Jenny Tarr, Jim Warshaw, Raphael |
author_facet | Dahlgren, James Takhar, Harpreet Anderson-Mahoney, Pamela Kotlerman, Jenny Tarr, Jim Warshaw, Raphael |
author_sort | Dahlgren, James |
collection | PubMed |
description | BACKGROUND: This is a community comparison study that examines persons living in a subdivision exposed to petroleum products and mercury. METHODS: We compared their health status and questionnaire responses to those living in another community with no known exposures of this type. RESULTS: Pristane house dust among the exposed homes was higher than in the comparison communities. The exposed subdivision has higher ambient air mercury levels compared to the control community. The prevalence of rheumatic diseases (OR = 10.78; CI = 4.14, 28.12) and lupus (OR = 19.33; CI = 1.96, 190.72) was greater in the exposed population compared to the unexposed. A higher prevalence of neurological symptoms, respiratory symptoms and several cardiovascular problems including stroke (OR = 15.41; CI = 0.78, 304.68) and angina (OR = 5.72; CI = 1.68, 19.43) was seen. CONCLUSION: There were statistically significant differences in B cells, Natural Killer Cells, gamma glutamyl transferase, globulin and serum calcium levels between control and exposed subjects. |
format | Text |
id | pubmed-1821321 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-18213212007-03-15 Cluster of systemic lupus erythematosus (SLE) associated with an oil field waste site: a cross sectional study Dahlgren, James Takhar, Harpreet Anderson-Mahoney, Pamela Kotlerman, Jenny Tarr, Jim Warshaw, Raphael Environ Health Research BACKGROUND: This is a community comparison study that examines persons living in a subdivision exposed to petroleum products and mercury. METHODS: We compared their health status and questionnaire responses to those living in another community with no known exposures of this type. RESULTS: Pristane house dust among the exposed homes was higher than in the comparison communities. The exposed subdivision has higher ambient air mercury levels compared to the control community. The prevalence of rheumatic diseases (OR = 10.78; CI = 4.14, 28.12) and lupus (OR = 19.33; CI = 1.96, 190.72) was greater in the exposed population compared to the unexposed. A higher prevalence of neurological symptoms, respiratory symptoms and several cardiovascular problems including stroke (OR = 15.41; CI = 0.78, 304.68) and angina (OR = 5.72; CI = 1.68, 19.43) was seen. CONCLUSION: There were statistically significant differences in B cells, Natural Killer Cells, gamma glutamyl transferase, globulin and serum calcium levels between control and exposed subjects. BioMed Central 2007-02-22 /pmc/articles/PMC1821321/ /pubmed/17316448 http://dx.doi.org/10.1186/1476-069X-6-8 Text en Copyright © 2007 Dahlgren et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Dahlgren, James Takhar, Harpreet Anderson-Mahoney, Pamela Kotlerman, Jenny Tarr, Jim Warshaw, Raphael Cluster of systemic lupus erythematosus (SLE) associated with an oil field waste site: a cross sectional study |
title | Cluster of systemic lupus erythematosus (SLE) associated with an oil field waste site: a cross sectional study |
title_full | Cluster of systemic lupus erythematosus (SLE) associated with an oil field waste site: a cross sectional study |
title_fullStr | Cluster of systemic lupus erythematosus (SLE) associated with an oil field waste site: a cross sectional study |
title_full_unstemmed | Cluster of systemic lupus erythematosus (SLE) associated with an oil field waste site: a cross sectional study |
title_short | Cluster of systemic lupus erythematosus (SLE) associated with an oil field waste site: a cross sectional study |
title_sort | cluster of systemic lupus erythematosus (sle) associated with an oil field waste site: a cross sectional study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1821321/ https://www.ncbi.nlm.nih.gov/pubmed/17316448 http://dx.doi.org/10.1186/1476-069X-6-8 |
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