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Intraneuronal Aβ immunoreactivity is not a predictor of brain amyloidosis-β or neurofibrillary degeneration

Amyloid β (Aβ) immunoreactivity in neurons was examined in brains of 32 control subjects, 31 people with Down syndrome, and 36 patients with sporadic Alzheimer’s disease to determine if intraneuronal Aβ immunoreactivity is an early manifestation of Alzheimer-type pathology leading to fibrillar plaqu...

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Detalles Bibliográficos
Autores principales: Wegiel, Jerzy, Kuchna, Izabela, Nowicki, Krzysztof, Frackowiak, Janusz, Mazur-Kolecka, Bozena, Imaki, Humi, Wegiel, Jarek, Mehta, Pankaj D., Silverman, Wayne P., Reisberg, Barry, deLeon, Mony, Wisniewski, Thomas, Pirttilla, Tuula, Frey, Harry, Lehtimäki, Terho, Kivimäki, Tarmo, Visser, Frank E., Kamphorst, Wouter, Potempska, Anna, Bolton, David, Currie, Julia R., Miller, David L.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1824787/
https://www.ncbi.nlm.nih.gov/pubmed/17237937
http://dx.doi.org/10.1007/s00401-006-0191-4