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Identification of a human TFPI-2 splice variant that is upregulated in human tumor tissues

BACKGROUND: Previous studies have shown that the expression of tissue factor pathway inhibitor-2 (TFPI-2), a matrix-associated Kunitz-type serine proteinase inhibitor, is markedly down-regulated in several tumor cells through hypermethylation of the TFPI-2 gene promoter. In the present study, RT-PCR...

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Detalles Bibliográficos
Autores principales: Kempaiah, Prakasha, Chand, Hitendra S, Kisiel, Walter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828166/
https://www.ncbi.nlm.nih.gov/pubmed/17352822
http://dx.doi.org/10.1186/1476-4598-6-20