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Population Genomics of the Immune Evasion (var) Genes of Plasmodium falciparum

Var genes encode the major surface antigen (PfEMP1) of the blood stages of the human malaria parasite Plasmodium falciparum. Differential expression of up to 60 diverse var genes in each parasite genome underlies immune evasion. We compared the diversity of the DBLα domain of var genes sampled from...

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Detalles Bibliográficos
Autores principales: Barry, Alyssa E, Leliwa-Sytek, Aleksandra, Tavul, Livingston, Imrie, Heather, Migot-Nabias, Florence, Brown, Stuart M, McVean, Gilean A. V, Day, Karen P
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828697/
https://www.ncbi.nlm.nih.gov/pubmed/17367208
http://dx.doi.org/10.1371/journal.ppat.0030034